CD107a / Lysosomal associated membrane protein 1 (LAMP1) Antibody
Product Sizes
100 ug
£671.00
3916-MSM2-P1-100UG
About this Product
- SKU:
- 3916-MSM2-P1
- Additional Names:
- CD107 antigen-like family member A
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- LAMP1/7457
- Clonality:
- Monoclonal
- Extra Details:
- Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107a) and LAMP-2 (also designated CD107b) are involved in a variety of functions; including cellular adhesion; and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans-Golgi network and are transported intracellularly via a pathway that is distinct from the Clathrincoated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of Thrombin-activated but not resting platelets; and it is thought to be involved in the adhesive; prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion; and their expression is increased in patients with lysosomal storage disorders.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa200-400) of human LAMP1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 120 kDa
- Research Area:
- Hematopoietic Stem Cells; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133954
