Laminin; gamma 1 (LAMC1) Antibody
Product Sizes
100 ug
£671.00
3915-MSM2-P1ABX-100UG
About this Product
- SKU:
- 3915-MSM2-P1ABX
- Additional Names:
- Laminin B2 chain | Laminin-1 subunit gamma | Laminin-10 subunit gamma | Laminin-11 subunit gamma | Laminin-2 subunit gamma | Laminin-3 subunit gamma | Laminin-4 subunit gamma | Laminin-6 subunit gamma | Laminin-7 subunit gamma | Laminin-8 subunit gamma | Laminin-9 subunit gamma | S-laminin subunit gamma
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- LAMC1/3162
- Clonality:
- Monoclonal
- Extra Details:
- Laminins are large hetero-trimeric; non-collagenous glycoproteins composed of alpha; beta; and gamma chains. This MAb reacts with laminin B2/1 chain of ~210kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components; some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN); entactin/nidogen (EN); collagen type IV (CIV); and large heparan sulfate proteoglycan (HSPG); which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity; from local discontinuities up to complete loss; are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.
- Host:
- Mouse
- Immunogen:
- Murine EHS laminin preparation
- Isotype:
- IgG1
- Molecular Weight:
- 210kDa
- Research Area:
- Cardiovascular; Complement System; Developmental Biology; Lung Cancer; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117361
