Recombinant CD171 / NCAM-L1 (L1 Cell Adhesion Molecule) Antibody
Product Sizes
20 ug
£364.00
3897-MSM8-P0-20UG
About this Product
- SKU:
- 3897-MSM8-P0
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rL1CAM/9163
- Clonality:
- Monoclonal
- Extra Details:
- L1 (L1 cell adhesion molecule) also known as CAML1; CD171; and HSAS is an adhesion molecule which plays an important role in the nervous system development; including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia; retardation; aphasia; spastic paraplegia and hydrocephalus). This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human L1CAM protein
- Isotype:
- IgG2b
- Molecular Weight:
- full-length isoforms: 140/180/220kDa; proteolytically cleaved form:85 kDa
- Research Area:
- Cardiovascular; Developmental Biology; Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=135885
