CD171 / NCAM-L1 (L1 Cell Adhesion Molecule) Antibody
Product Sizes
100 ug
£671.00
3897-MSM1X-P1-100UG
About this Product
- SKU:
- 3897-MSM1X-P1
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- SPM275
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a cell surface protein of 220-240kDa; identified as L1 cell adhesion molecule. The L1CAM gene; which is located in Xq28; is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation; aphasia; shuffling gait; and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1; neural cell adhesion molecule (L1CAM) also plays an important role in axon growth; fasciculation; and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
- Host:
- Mouse
- Immunogen:
- Homogenous suspension of 16-week human fetal brain
- Isotype:
- IgG1
- Molecular Weight:
- 220-240kDa
- Research Area:
- Autophagy; Cardiovascular; Developmental Biology; Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117336
