CD171 / NCAM-L1 (Axonal Marker) Antibody

Product Sizes

100 ug

£671.00

3897-MSM1-P1ABX-100UG

About this Product

SKU:: 3897-MSM1-P1ABX
Application:: ELISA
translate.label.attr.clone:: UJ127
Clonality:: Monoclonal
Extra Details:: Recognizes a cell surface protein of 220-240kDa; identified as L1 cell adhesion molecule. The L1CAM gene; which is located in Xq28; is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation; aphasia; shuffling gait; and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1; neural cell adhesion molecule (L1CAM) also plays an important role in axon growth; fasciculation; and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
Host:: Mouse
Immunogen:: Homogenous suspension of 16-week human fetal brain
Isotype:: IgG1
Molecular Weight:: 220-240kDa
Research Area:: Autophagy; Cardiovascular; Developmental Biology; Neuroscience
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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