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Antibodies

Recombinant Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker) Antibody

Product Sizes
100 ug
£671.00
3866-RBM15-P1-100UG
About this Product
SKU:
3866-RBM15-P1
Additional Names:
Cytokeratin-15 | Keratin-15
Application:
Immunohistochemistry
translate.label.attr.clone:
KRT15/9088R
Clonality:
Monoclonal
Extra Details:
Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. KRT15 is downregulated in activated keratinocytes. It is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma; sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19; and absence of hair keratins.
Host:
Rabbit
Immunogen:
Recombinant human full-length KRT15 protein
Isotype:
IgG
Molecular Weight:
52kDa
Research Area:
Basal Cell Marker; Developmental Biology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody