Cytokeratin 14 (Squamous Cell Marker) Antibody
Product Sizes
100 ug
£671.00
3861-MSM1X-P1ABX-100UG
About this Product
- SKU:
- 3861-MSM1X-P1ABX
- Additional Names:
- Cytokeratin-14 | Keratin-14
- Application:
- Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- SPM263
- Clonality:
- Monoclonal
- Extra Details:
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia; some glandular epithelia; myoepithelium; and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore; this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics; and in identifying metaplastic carcinomas of the breast.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
- Isotype:
- IgG3
- Molecular Weight:
- ~50kDa
- Research Area:
- Autophagy; Basal Cell Marker; Developmental Biology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117124
