Recombinant Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) Antibody
Product Sizes
20 ug
£364.00
3860-MSM8-P0-20UG
About this Product
- SKU:
- 3860-MSM8-P0
- Additional Names:
- Cytokeratin-13 | Keratin-13
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rKRT13/9623
- Clonality:
- Monoclonal
- Extra Details:
- Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs)that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation; which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with Cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN); a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft; white and spongy plaques in the oral mucosa.
- Host:
- Mouse
- Immunogen:
- esophageal keratins of rabbit origin
- Isotype:
- IgG2b
- Molecular Weight:
- 52kDa
- Research Area:
- Developmental Biology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=137027
