Recombinant Cytokeratin 10 (Suprabasal Epithelial Marker) Antibody
Product Sizes
100 ug
£671.00
3858-MSM7-P1ABX-100UG
About this Product
- SKU:
- 3858-MSM7-P1ABX
- Additional Names:
- Cytokeratin-10 | Keratin-10
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rKRT10/1275
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of 56.5kDa; identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis; expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer; appears in the first suprabasal layers and increases in concentration towards the granular layer. However; CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm; clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm; clinical stages II and III); CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes; being preferentially detected in more-differentiated parts.
- Host:
- Mouse
- Immunogen:
- Recombinant full-lenth human KRT10 protein.
- Isotype:
- IgG1
- Molecular Weight:
- 56.5kDa
- Research Area:
- Autophagy; Developmental Biology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=117067
