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Antibodies

Cytokeratin 6A (KRT6A) (Basal Cell Marker) Antibody

Product Sizes
100 ug
£671.00
3853-MSM4-P1-100UG
About this Product
SKU:
3853-MSM4-P1
Additional Names:
Cytokeratin-6A | Cytokeratin-6D | Keratin-6A | Type-II keratin Kb6
Application:
Flow Cytometry, Immunohistochemistry
translate.label.attr.clone:
KRT6A/2368
Clonality:
Monoclonal
Extra Details:
This MAb recognizes a protein of 56kDa; identified as cytokeratin 6A (KRT6A). In humans; multiple isoforms of Cytokeratin 6 (6A-6F); encoded by several highly homologous genes; have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes; which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles; suprabasal cells of a variety of internal stratified epithelia; in epidermis; in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes; which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas..
Host:
Mouse
Immunogen:
Recombinant full-length human Cytokeratin 6A (KRT6A)protein
Isotype:
IgG2a
Molecular Weight:
56kDa
Research Area:
Developmental Biology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody