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Antibodies

Cytokeratin 5 (KRT5) (Basal; Myoepithelial & Mesothelial Cell Marker) Antibody

Product Sizes
0.1 ml
3852-MSM1-CS0-0.1ML
About this Product
SKU:
3852-MSM1-CS0
Additional Names:
58 kDa cytokeratin | Cytokeratin-5 | Keratin-5 | Type-II keratin Kb5
Application:
Immunohistochemistry
translate.label.attr.clone:
KRT5/2080
Clonality:
Monoclonal
Extra Details:
This MAb recognizes a protein of 58kDa; which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia; myoepithelia; and mesothelium.Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas; half of transitional carcinomas; and many undifferentiated large cell carcinomas express.Anti-KRT5; along with anti-p63; affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast; glandular epithelia; and basal cells of the prostate are labeled with anti-KRT5.
Host:
Mouse
Immunogen:
Recombinant human Cytokeratin 5 (KRT5) protein fragment (around aa 318-491) (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
58kDa
Research Area:
Basal Cell Marker; Developmental Biology
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody