CD161 / KLRB1 (Killer cell lectin like receptor B1) Antibody
Product Sizes
100 ug
£671.00
3820-MSM1-P1ABX-100UG
About this Product
- SKU:
- 3820-MSM1-P1ABX
- Additional Names:
- C-type lectin domain family 5 member B | HNKR-P1a | Natural killer cell surface protein P1A
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- KLRB1/8910
- Clonality:
- Monoclonal
- Extra Details:
- Natural killer (NK) and T cells express a superfamily of proteins with structural features of C-type lectins. T cells bearing natural killer receptors (NKRs) such as CD94 and CD161 are present in psoriasis. CD161 mediates NK cell activation and functions as an activating receptor. CD161 is a prototypic marker of NK cells; although it is also found on a subset of CD8+ T cells. The expression of NK receptors on CD8+ T cells can be considered a marker of cytotoxic effector T cells that are expanded in vivo after antigenic activation leading to extensive proliferation. The transcription; mRNA accumulation; and surface expression of CD161; a molecule involved in triggering cytotoxicity; is specifically upregulated by IL-12.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-225) of human KLRB1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 25kDa
- Research Area:
- Hematopoietic Stem Cells; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=135884
