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Antibodies

Recombinant CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) Antibody

Product Sizes
100 ug
£671.00
3815-RBM22-P1ABX-100UG
About this Product
SKU:
3815-RBM22-P1ABX
Additional Names:
Piebald trait protein | Proto-oncogene c-Kit | Tyrosine-protein kinase Kit | p145 c-kit | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Application:
ELISA, Immunohistochemistry
translate.label.attr.clone:
C117/8879R
Clonality:
Monoclonal
Extra Details:
This MAb recognizes a protein of 145kDa; identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid; adenocarcinomas from endometrium; lung; ovary; pancreas; and breast as well as malignant melanoma; endodermal sinus tumor; and small cell carcinoma. However; anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi s sarcoma; tumors of smooth muscle origin; fibromatosis; and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Host:
Rabbit
Immunogen:
Recombinant fragment (around aa 1-200) of human KIT protein (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
~145kDa
Research Area:
AKT Signaling; Breast Cancer; Cardiac Stem Cells; Cardiovascular; Dendritic Cell Marker; Hematopoietic Stem Cells; Infectious Disease; Mast Cell Marker; Mesenchymal Stem Cell Differentiation; Signal T
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody