B7-H6 / NCR3LG1 (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1) Antibody
Product Sizes
100 ug
£671.00
374383-MSM1-P1ABX-100UG
About this Product
- SKU:
- 374383-MSM1-P1ABX
- Additional Names:
- B7 homolog 6
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- B7H6/4821
- Clonality:
- Monoclonal
- Extra Details:
- B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa38-169) of human NCR3LG protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 51kDa
- Research Area:
- Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116767
