Catenin; gamma (Cardiomyocyte Marker) Antibody
Product Sizes
100 ug
£671.00
3728-MSM1-P1-100UG
About this Product
- SKU:
- 3728-MSM1-P1
- Additional Names:
- Catenin gamma | Desmoplakin III | Desmoplakin-3
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- [11E4]
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of 80-87kDa; identified as gamma-catenin. The catenins (; ; and ) are ubiquitously expressed; cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. T-catenin; also referred to as VR22; is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. T-catenin binds to E-catenin as well as to -catenin; and it functions to inhibit Wnt signaling. CTNNA3; the gene that encodes for -T-catenin; is located on chromosome 10; and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.
- Host:
- Mouse
- Immunogen:
- Recombinant full length human plakoglobin; fused to maltose binding protein
- Isotype:
- IgG1
- Molecular Weight:
- 80-87kDa
- Research Area:
- Autophagy; Cardiovascular; Developmental Biology; Immunology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116761
