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Antibodies

JunB / Transcription Factor JunB Antibody

Product Sizes
100 ug
£671.00
3726-MSM1-P1-100UG
About this Product
SKU:
3726-MSM1-P1
Additional Names:
Transcription factor AP-1 subunit JunB
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
PCRP-JUNB-3G11
Clonality:
Monoclonal
Extra Details:
The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein; along with c-Fos; is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes; Jun B and Jun D; have been shown to be almost identical to c-Jun in their C-terminal regions; which are involved in dimerization and DNA binding; whereas their N-terminal domains; which are involved in transcriptional activation; diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
Host:
Mouse
Immunogen:
Recombinant full-length human JUNB protein
Isotype:
IgG2c
Molecular Weight:
35.8kDa
Research Area:
Cytokine Signaling; Immunology; Infectious Disease; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody