Recombinant CD61 / Integrin 3 / Platelet Glycoprotein IIIa (Platelet Marker) Antibody
Product Sizes
100 ug
£671.00
3690-RBM6-P1-100UG
About this Product
- SKU:
- 3690-RBM6-P1
- Additional Names:
- Platelet membrane glycoprotein IIIa
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- ITGB3/2166R
- Clonality:
- Monoclonal
- Extra Details:
- Reacts with human integrin beta3 (GPIIIa; vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor; soluble fibrinogen; fibronectin; vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow; as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
- Host:
- Rabbit
- Immunogen:
- Recombinant human ITGB3 protein fragment (aa 385-490) (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 105kDa & 90kDa
- Research Area:
- AKT Signaling; Angiogenesis; Cardiovascular; Complement System; Developmental Biology; Endothelial Cell Marker; Hematopoietic Stem Cells; Infectious Disease; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116705
