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Antibodies

CD11a / Integrin L / LFA-1 Chain Antibody

Product Sizes
100 ug
£671.00
3683-MSM2-P1ABX-100UG
About this Product
SKU:
3683-MSM2-P1ABX
Additional Names:
CD11 antigen-like family member A | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
DF1524
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 180kDa; identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family; CD18; to form the cell surface heterodimer; LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes; monocytes; and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54); ICAM-2 (CD102); ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.
Host:
Mouse
Immunogen:
Human CD11a protein
Isotype:
IgG2b
Molecular Weight:
180kDa
Research Area:
AKT Signaling; BBB VCAM-1 Signaling; Cardiovascular; Hematopoietic Stem Cells; Immunology; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody