Recombinant CD103 / Integrin αEβ7 (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody

Product Sizes

100 ug

£671.00

3682-RBM6-P1ABX-100UG

About this Product

SKU:: 3682-RBM6-P1ABX
Additional Names:: HML-1 antigen | Integrin alpha-IEL | Mucosal lymphocyte 1 antigen
Application:: Immunohistochemistry
translate.label.attr.clone:: ITGAE/3904R
Clonality:: Monoclonal
Extra Details:: This MAb recognizes a protein of 150kDa; identified as CD103; which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells; whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions; such as T-cell lymphomas and hairy cell leukemia (HCL); the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
Host:: Rabbit
Immunogen:: Recombinant human ITGAE/CD103 protein fragment (aa 775-855) (exact sequence is proprietary)
Isotype:: IgG
Molecular Weight:: 150kDa
Research Area:: AKT Signaling; Dendritic Cell Marker
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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