Androgen Receptor (Marker of Androgen Dependence) Antibody
Product Sizes
20 ug
£364.00
367-MSM1X-P0-20UG
About this Product
- SKU:
- 367-MSM1X-P0
- Additional Names:
- Dihydrotestosterone receptor | Nuclear receptor subfamily 3 group C member 4
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- SPM335
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 110kDa; which is identified as androgen receptor (AR). It reacts with full length; and the newly described A form of the receptor. It does not cross react with estrogen; progesterone; or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer; AR has been proposed; as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide; aa 302-318 (STEDTAEYSPFKGGYTK) of human AR
- Isotype:
- IgG1
- Molecular Weight:
- 110kDa
- Research Area:
- AKT Signaling; Cancer; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116583
