Recombinant MUM1 / IRF4 (Transcription Factor) Antibody
Product Sizes
100 ug
£671.00
3662-RBM4-P1-100UG
About this Product
- SKU:
- 3662-RBM4-P1
- Additional Names:
- Lymphocyte-specific interferon regulatory factor | Multiple myeloma oncogene 1 | NF-EM5
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MUM1/8274R
- Clonality:
- Monoclonal
- Extra Details:
- MUM1 is one of nuclear transcription factors necessary for development and activation of B lymphocytes. MUM1 belongs to the IRF gene family containing at least 10 widely expressed genes with similar DNA binding motif all involved in regulation of cell growth; transformation and induction of apoptosis as well as development of T-cell immune response. The synonym of MUM1 is Interferon Regulatory Factor 4 (IRF4). MUM1 is found mainly in B-cell lymphoma and melanocytic lesions. Significant variation in positivity mainly due to chromosomal translocations involving MUM1 gene among T-cell lymphomas is observed. MUM1 is useful in a panel with other markers for subclassification of malignant lymphomas and identification of plasma cell differentiation. Particularly MUM1 may be useful for the identification of plasma cell differentiation when morphologic evidence is lacking and Ig light chains are difficult to interpret.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (corresponding to C-terminal) of IRF4 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 52kDa
- Research Area:
- Cytokine Signaling; Immunology; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. ;Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127730
