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Antibodies

Insulin / IRDN (beta-Cell & Insulinoma Marker) Antibody

Product Sizes
20 ug
£364.00
3630-MSM2-P0-20UG
About this Product
SKU:
3630-MSM2-P0
Application:
Immunohistochemistry
translate.label.attr.clone:
E2-E3; same as INS04
Clonality:
Monoclonal
Extra Details:
Recognizes a polypeptide which is identified as insulin; a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin; which has very little biological activity; is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose; amino acids; and certain ions. It also promotes glycogen storage; formation of triglycerides; and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Host:
Mouse
Immunogen:
Purified pig insulin; conjugated to KLH
Isotype:
IgG1
Molecular Weight:
6kDa
Research Area:
Autophagy; Cardiovascular; Developmental Biology; Mesenchymal Stem Cell Differentiation; Signal Transduction; Stem Cell Differentiation; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody