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Antibodies

Inhibin; alpha (INHA) (Gonadal Cell Marker) Antibody

Product Sizes
20 ug
£364.00
3623-MSM1-P0-20UG
About this Product
SKU:
3623-MSM1-P0
Application:
Immunohistochemistry
translate.label.attr.clone:
INHA/1168
Clonality:
Monoclonal
Extra Details:
It recognizes a 47kDa protein; which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits; Inhibin A and Inhibin B. Each subunit consists of the same 伪 subunit; covalently linked to 1 of 2 distinct subunits; 尾-伪 or 尾-尾. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein; inhibin belongs to the transforming growth factor 尾 (TFG尾) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.
Host:
Mouse
Immunogen:
Recombinant fragment of human Inhibin alpha protein (around aa 233-362) (exact sequence is proprietary)
Isotype:
IgG2b
Molecular Weight:
47kDa
Research Area:
Cardiovascular
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody