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Antibodies

CD137 / 4-1BB / TNFRSF9 Antibody

Product Sizes
100 ug
£671.00
3604-MSM1-P1-100UG
About this Product
SKU:
3604-MSM1-P1
Additional Names:
4-1BB ligand receptor | CDw137 | T-cell antigen 4-1BB homolog | T-cell antigen ILA
Application:
ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
4-1BB/3201
Clonality:
Monoclonal
Extra Details:
CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells; macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment; and has been implicated in breast cancer; melanoma and lymphoma.
Host:
Mouse
Immunogen:
A recombinant fragment (around aa 19-188) of human CD137 protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
32kDa (monomer); 85kDa (dimer)
Research Area:
AKT Signaling; B Cell Markers; Cardiovascular; Cytokine Signaling; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody