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Antibodies

Recombinant Interleukin-15 (IL-15) Antibody

Product Sizes
100 ug
£671.00
3600-RBM11-P1-100UG
About this Product
SKU:
3600-RBM11-P1
Application:
Immunohistochemistry
translate.label.attr.clone:
IL15/6971R
Clonality:
Monoclonal
Extra Details:
Interleukin-15 (IL-15); also designated IL-T; is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human; mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells; while enhancing B cell expansion and antibody production. Unlike IL-2; IL-15 is not produced by lymphocytes; but appears to be produced by macrophages; epithelial lines; muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the 尾 signaling subunit of the IL-2R. Evidence also suggests that like IL-2; IL-4 and IL-7; IL-15 utilizes the common IL-2R纬 subunit.
Host:
Rabbit
Immunogen:
Recombinant fragment of human IL15 (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
14-15kDa
Research Area:
AKT Signaling; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immunology; Nuclear Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody