Interleukin 10 (IL10) (Immuno-regulation Marker) Antibody
Product Sizes
20 ug
£364.00
3586-MSM2-P0-20UG
About this Product
- SKU:
- 3586-MSM2-P0
- Additional Names:
- Cytokine synthesis inhibitory factor
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- IL10/8711
- Clonality:
- Monoclonal
- Extra Details:
- Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines; MHC class II antigens; and costimulatory molecules on macrophages. It also enhances B cell survival; proliferation; and antibody production. This cytokine can block NF-kappa B activity; and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human Interleukin 10 (IL10) protein
- Isotype:
- IgG1
- Molecular Weight:
- 20kDa (Monomer); 37kDa (Dimer)
- Research Area:
- AKT Signaling; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immunology; Infectious Disease; Neuroinflammation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=134713
