Interleukin-7 (IL-7) Antibody
Product Sizes
20 ug
£364.00
3574-MSM3-P0-20UG
About this Product
- SKU:
- 3574-MSM3-P0
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- IL7/4013
- Clonality:
- Monoclonal
- Extra Details:
- Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells; thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor specific chain and the IL-2 receptor 纬 chain common to the IL-2; IL-4; IL-7; IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells; the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of Insulin receptor substrate-1 (IRS-1) and Insulin receptor substrate-2 (IRS-2); originally called 4PS.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 27-177) corresponding to mature protein of human IL7(exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 25kDa
- Research Area:
- AKT Signaling; B Cell Markers; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116406
