IL6ST / CD130 / Interleukin 6 Signal Transducer / IL6RB Antibody
Product Sizes
20 ug
£364.00
3572-MSM1-P0-20UG
About this Product
- SKU:
- 3572-MSM1-P0
- Additional Names:
- CDw130 | Interleukin-6 signal transducer | Membrane glycoprotein 130 | Oncostatin-M receptor subunit alpha
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- IL6ST/4101
- Clonality:
- Monoclonal
- Extra Details:
- Interleukin-5; or IL-5; was originally discovered as a soluble T cell-derived factor; called T cell-replacing factor (TRF); that induced T cell-depleted activated B cells to secrete immunoglobulin. Native IL-5 is a disulfide-linked homodimer. IL-5 is initially synthesized as a precursor with a 19 amino acid signal peptide which is cleaved to form a 112 amino acid mature protein. Murine and human IL-5 exhibit 70% sequence identity at the amino acid level. IL-5 exerts its biological activity through the IL-5 receptor (IL-5R); which is composed of at least two chains: an chain that binds IL-5 with low affinity and a chain that does not bind IL-5; but together with the IL-5 a chain; constitutes the high affinity IL-5 receptor. The chain is common to the IL-3; IL-5 and GM-CSF receptors and has been shown to signal through the JAK/Stat pathway.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human IL6ST protein corresponding to extracellular domain(exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 103kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immunology; Neuroinflammation; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116404
