IL-4 / Interleukin 4 Antibody
Product Sizes
100 ug
£671.00
3565-MSM1-P1ABX-100UG
About this Product
- SKU:
- 3565-MSM1-P1ABX
- Additional Names:
- B-cell stimulatory factor 1 | Binetrakin | Lymphocyte stimulatory factor 1 | Pitrakinra
- Application:
- ELISA
- translate.label.attr.clone:
- IL4/1597
- Clonality:
- Monoclonal
- Extra Details:
- Interleukin-4 (IL-4); also designated B cell stimulatory factor-1; is a glycosylated cytokine secreted by activated T lymphocytes; basophils and mast cells. The secreted IL-4 protein promotes the growth and differentiation of cells that participate in immune defense by favoring such events as the expansion of the Th2 lineage relative to Th1 cells. These T helper cell subsets are defined by their pattern of cytokine secretion: Th1 cells secrete IL-2; TNF; while Th2 cells secrete IL-4; IL-5 and IL-10. Another key immunological function of IL-4 is to induce immunoglobulin class switching. IL-4 has been shown to induce the production of IgE and enhance IgG4 secretion by B cells; but suppress the production of IgM; IgA; IgG1; IgG2 and IgG3. It has been determined that Stat6 is rapidly tyrosine phosphorylated following stimulation of IL-3 or IL-4; but is not detectably phosphorylated following stimulation with IL-2; IL-12 or erythropoietin.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human IL-4 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 18kDa
- Research Area:
- AKT Signaling; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immunology; Mast Cell Marker; Neuroinflammation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116400
