CD25 / IL2RA (Activated Lymphocyte Marker) Antibody
Product Sizes
100 ug
£671.00
3559-MSM3-P1-100UG
About this Product
- SKU:
- 3559-MSM3-P1
- Additional Names:
- TAC antigen | p55
- Application:
- ELISA, Western Blot
- translate.label.attr.clone:
- IL2RA/2393
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 55kDa; identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas; CD25 is present on malignant cells of Hodgkin's disease; HTLV-1+ adult T-cell leukemia; cutaneous T-cell lymphoma; and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain; p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions; A; B and C. This MAb recognizes the epitope B; which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotype:
- IgG2b
- Molecular Weight:
- 55kDa
- Research Area:
- AKT Signaling; B Cell Markers; Cardiovascular; Cytokine Signaling; Hematopoietic Stem Cells; Immune checkpoint; Immunology; Mast Cell Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116343
