Interleukin-1 alpha (IL-1 alpha) Antibody
Product Sizes
100 ug
£671.00
3552-MSM2-P1ABX-100UG
About this Product
- SKU:
- 3552-MSM2-P1ABX
- Additional Names:
- Hematopoietin-1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- IL1A/3982
- Clonality:
- Monoclonal
- Extra Details:
- Two forms of interleukin-1; designated IL-1伪and IL-1尾; have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity; IL-1伪 and IL-1尾 bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation; but it has also been shown to be expressed during kidney development; thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation; acting as an activator of T and B lymphocytes and natural killer (NK) cells. In T cells; IL-1 stimulates the production of IL-2 and selectively inhibits IL-4 expression. IL-1 induces B cell proliferation and maturation; and immunoglobulin synthesis. NK cells require IL-1尾 for production of the anti-pathogen IFN-纬. IL-1 has also been implicated in several pathological conditions including rheumatoid arthritis; inflammatory bowel disease and atherosclerosis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 113-271) of human IL1A protein
- Isotype:
- IgG2b
- Molecular Weight:
- 33kDa (proprotein); 17kDa (mature)
- Research Area:
- AKT Signaling; Cardiovascular; Cytokine Signaling; Endothelial Cell Marker; Immunology; Infectious Disease; MAPK Signaling; Neuroinflammation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116287
