Recombinant CD95 / FAS / TNFRSF6 (Marker of Cancer Associated Fibroblasts) Antibody
Product Sizes
100 ug
£671.00
355-MSM21-P1ABX-100UG
About this Product
- SKU:
- 355-MSM21-P1ABX
- Additional Names:
- Apo-1 antigen | Apoptosis-mediating surface antigen FAS | FASLG receptor
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rGM30
- Clonality:
- Monoclonal
- Extra Details:
- Fas; also known as CD95 antigen; is a 48 kD transmembrane glycoprotein. It is a member of the nerve growth factor receptor/tumor necrosis factor superfamily. This cell surface molecule mediates receptor-triggered apoptosis (programmed cell death). During embryonic and postembryonic development; many cells die by means of programmed cell death; which plays a major role in determining morphological and functional maturity in a variety of systems; including the formation of the neural network and clonal deletion of autoreactive T cells. Apoptosis is accompanied by condensation of the cytoplasm; loss of plasma membrane microvilli and extensive degradation of chromosomal DNA into oligomers of about 180 base pairs. The Fas antigen is expressed on the surface of various cell types; including activated T and B lymphocytes and T lymphoblastoid cell lines.
- Host:
- Mouse
- Immunogen:
- Prokaryotic recombinant fusion protein corresponding to the internal domain near the C-terminal end of the human Fas molecule
- Isotype:
- IgG1
- Molecular Weight:
- 38-50kDa
- Research Area:
- AKT Signaling; Apoptosis; Autophagy; Cardiovascular; Complement System; Endothelial Cell Marker; MAPK Signaling; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=141428
