Recombinant Prostate Specific Antigen (PSA) Antibody
Product Sizes
100 ug
£671.00
354-RBM18-P1-100UG
About this Product
- SKU:
- 354-RBM18-P1
- Additional Names:
- Gamma-seminoprotein | Kallikrein-3 | P-30 antigen | Semenogelase
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- KLK3/7128R
- Clonality:
- Monoclonal
- Extra Details:
- Prostate-specific antigen (PSA) is a single-chain glycoprotein of 237 amino acids containing approximately 8% carbohydrate. It is a serine protease produced almost exclusively by prostatic epithelial cells.Immunohistochemically PSA is expressed in the highly specialized apically-superficial layer of female and male secretory cells of the prostate gland; and is readily demonstrated in adenocarcinomas of the prostate in about 99% of the cases. There is a correlation between malignancy grade and intensity of staining; high grade carcinomas displaying weaker expression. About 1% of poorly differentiated carcinomas have been negative for PSA.Due to the high specificity of PSA for prostatic glandular epithelium; it is very useful in identifying prostatic carcinoma in the prostate and in the adjacent organs often affected by epithelial malignancies; i.e. rectum and urinary bladder. PSA may be used in a panel together with NKX3.1 and Prostein; which are at least as sensitive and slightly more specific than PSA.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa150-250) of human KLK3 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 29kDa
- Research Area:
- Cardiovascular; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116281
