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Antibodies

Lambda Light Chain (B-Cell Marker) Antibody

Product Sizes
20 ug
£364.00
3535-MSM5-P0-20UG
About this Product
SKU:
3535-MSM5-P0
Additional Names:
Ig lambda chain V-I region BL2 | Ig lambda chain V-I region EPS | Ig lambda chain V-I region NEW | Ig lambda chain V-I region NIG-64
Application:
Flow Cytometry, Immunofluorescence, Western Blot
translate.label.attr.clone:
LcN-2 + ICO-106
Clonality:
Monoclonal
Extra Details:
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals; the two light chains in an antibody are always identical; with only one type of light chain; kappa or lambda. The ratio of Kappa to Lambda is 70:30. However; with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias; plasmacytomas; and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Host:
Mouse
Immunogen:
Purified human IgG (LcN-2 and ICO-106)
Isotype:
IgG1; IgG2a
Molecular Weight:
~22.5kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody