beta Amyloid Antibody
Product Sizes
100 ug
£671.00
351-MSM5-P1ABX-100UG
About this Product
- SKU:
- 351-MSM5-P1ABX
- Additional Names:
- ABPP | APPI | Alzheimer disease amyloid A4 protein homolog | Alzheimer disease amyloid protein | Amyloid precursor protein | Amyloid-beta (A4) precursor protein | Amyloid-beta A4 protein | Cerebral vascular amyloid peptide | PreA4 | Protease nexin-II
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- APP/3345
- Clonality:
- Monoclonal
- Extra Details:
- Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the 尾-Amyloid and Amyloid A4 proteins; which are present in human platelets. Amyloid deposition is associated with type II diabetes; Down syndrome and a variety of neurological disorders; including Alzheimer s disease. The Amyloid precursor protein (APP) undergoes alternative splicing; resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid 尾/A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa578-680) of human Amyloid Beta protein (exact sequence is proprietary)
- Isotype:
- IgG2c
- Molecular Weight:
- 4-46kDa (å°¾-Amyloid); 100-125kDa (Amyloid A4)
- Research Area:
- Cardiovascular; Cytokine Signaling; Defective Intrinsic Apoptosis; Immunology; Infectious Disease; Neuroscience; Ovarian Cancer; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=116105
