IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker) Antibody
Product Sizes
20 ug
£364.00
3495-MSM1-P0-20UG
About this Product
- SKU:
- 3495-MSM1-P0
- Additional Names:
- Ig delta chain C region | Ig delta chain C region NIG-65 | Ig delta chain C region WAH
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- IgD26
- Clonality:
- Monoclonal
- Extra Details:
- Immunoglobulins are four-chain; Y-shaped; monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains; the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule; co-expressed with IgM on the surface of mature/naive B cells. In particular; it is found on spleen B cell surfaces. Compared to IgM; IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice; the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
- Host:
- Mouse
- Immunogen:
- Full-length human IGHD protein
- Isotype:
- IgG1
- Molecular Weight:
- 44-80kDa (heavy chain); 21-25kDa (kappa light chain)
- Research Area:
- B Cell Markers
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115981
