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Antibodies

IGFBP3 Antibody

Product Sizes
100 ug
£671.00
3486-MSM4-P1ABX-100UG
About this Product
SKU:
3486-MSM4-P1ABX
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
IGFBP3/3424
Clonality:
Monoclonal
Extra Details:
The Insulin-like growth factor-binding proteins; or IGFBPs; are a family of homologous proteins that have co-evolved with the IGFs. They serve not only as shuttle molecules for the soluble IGFs; but also confer a level of regulation to the IGF signaling system. Physical association of the IGFBPs with IGF influences the bio-availability of the growth factors; as well as their concentration and distribution in the extracellular environment. In addition; the IGFBPs appear to have biological activity independent of the IGFs. Seven IGFBPs have thus far been described; each differing in their tissue distribution; half-lives and modulation of IGF interactions with their receptors. IGFBP3 is the most abundant IGFBP and is complexed with roughly 80% of the serum IGFs. Both IGFBP3 and IGFBP4 are released by dermal fibroblasts in response to incision injury.
Host:
Mouse
Immunogen:
Recombinant human full-lengthIGFBP3protein
Isotype:
IgG2b
Molecular Weight:
40/44kDa
Research Area:
Cardiovascular; Mesenchymal Stem Cell Differentiation; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody