CD50 / ICAM3 Antibody
Product Sizes
100 ug
£671.00
3385-MSM3-P1ABX-100UG
About this Product
- SKU:
- 3385-MSM3-P1ABX
- Additional Names:
- CDw50 | ICAM-R
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry
- translate.label.attr.clone:
- 101-1D2
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds; identified as CD50 or ICAM-3 (WS: IV V). Its epitope localizes in the D2 extracellular domain and is resistant to neuraminidase and proteases. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signalling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb inhibits primary mixed lymphocyte culture (MLC) but not secondary MLC; cytotoxicity or proliferation induced by mitogens. It blocks binding of NK1-L16 stimulated T cells to L cells expressing CD50. This MAb is excellent for staining of formalin/paraffin tissues.
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotype:
- IgG2a
- Molecular Weight:
- 110-160kDa
- Research Area:
- Cardiovascular; Immunology; Mitochondria Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115802
