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Antibodies

CD54 / ICAM-1 Antibody

Product Sizes
20 ug
£364.00
3383-MSM8-P0-20UG
About this Product
SKU:
3383-MSM8-P0
Additional Names:
Major group rhinovirus receptor
Application:
Immunohistochemistry
translate.label.attr.clone:
ICAM1/6968
Clonality:
Monoclonal
Extra Details:
Recognizes an 85-115kDa protein (variation with cell type); identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family; present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts; EC; macrophages; and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule; LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.
Host:
Mouse
Immunogen:
Recombinant fragment of human ICAM1 (exact sequence is proprietary)
Isotype:
IgG2a
Molecular Weight:
85-115kDa
Research Area:
BBB VCAM-1 Signaling; Cardiovascular; Complement System; Cytokine Signaling; Endothelial Cell Marker; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody