HSP90AA1 (Heat Shock Protein 90) Antibody
Product Sizes
100 ug
£671.00
3320-MSM7-P1ABX-100UG
About this Product
- SKU:
- 3320-MSM7-P1ABX
- Additional Names:
- Heat shock 86 kDa | Lipopolysaccharide-associated protein 2 | Renal carcinoma antigen NY-REN-38
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- HSP90AA1/7247
- Clonality:
- Monoclonal
- Extra Details:
- The heat shock response was first described for Drosophila salivary gland cells and morphologically consists of a change in their polytene chromosome puffing patterns that involves de novo synthesis of a few proteins. Similar heat shock proteins were later discovered in bacterial chicken and mammalian cells; and have been subsequently studied in other organisms. A series of proteins including HSP 90; HSP 70; HSP 20-30 and ubiquitin are induced by insults such as temperature shock; chemicals and other environmental stress. A major function of HSP 90 and other HSPs is to act as molecular chaperones. HSP 90 forms a complex with glucocorticoid receptor (GR); rendering the non ligand-bound receptor transcriptionally inactive. HSP 90 binds the GR as a heterocomplex composed of either HSP 56 or Cyclophilin D; forming an aporeceptor comiplex. HSP 90 also exists as a dimer with other proteins such as p60/sti1 and p23; forming an apo-receptor complex with estrogen and androgen receptors.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa500-700) of human HSP90AA1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 90kDa
- Research Area:
- AKT Signaling; Cardiovascular; Cytokine Signaling; Developmental Biology; Immunology; Infectious Disease; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months.;Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=134686
