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Antibodies

HSP27 (Heat Shock Protein 27) Antibody

Product Sizes
100 ug
£671.00
3315-MSM1-P1-100UG
About this Product
SKU:
3315-MSM1-P1
Additional Names:
28 kDa heat shock protein | Estrogen-regulated 24 kDa protein | Heat shock 27 kDa protein | Stress-responsive protein 27
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
G3.1
Clonality:
Monoclonal
Extra Details:
MAb G3.1 reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27; also referred to as the Estrogen-Regulated 24K protein and HSP28; is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature; as well as by estrogen in hormone responsive cells. Interestingly; human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian alpha-crystalline lens protein. Because of the estrogen responsive nature of HSP27; this protein has been studied extensively in human estrogen responsive tissues such as cervix; endometrium and breast tissue. Therefore; HSP27 may be useful in classifying various hormone sensitive tumors.
Host:
Mouse
Immunogen:
Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.
Isotype:
IgG1
Molecular Weight:
27kDa
Research Area:
BBB VCAM-1 Signaling; MAPK Signaling; Ovarian Cancer; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody