Serum Amyloid P / APCS Antibody
Product Sizes
100 ug
£671.00
325-MSM1-P1ABX-100UG
About this Product
- SKU:
- 325-MSM1-P1ABX
- Additional Names:
- 9.5S alpha-1-glycoprotein
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- APCS/3240
- Clonality:
- Monoclonal
- Extra Details:
- Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins; which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells; SAP is found in serum and urine. Although the function of SAP has not been clearly established; it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2; SAP is a precursor of the protein amyloid P component (AP); which is universally associated with the amyloid deposits in all forms of amyloidoses; including Alzheimer s disease. SAP is a decamer of ten identical; noncovalently linked subunits; each of which may be post-translationally modified by glycosylation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human APCS protein (around aa 143-223) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 200kDa (oligomeric); 26kDa (non-covalently bound subunit); 30kDa (glycosylated SAP subunit)
- Research Area:
- Cardiovascular; Complement System
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115597
