FOXA1 / HNF3A Antibody
Product Sizes
20 ug
£364.00
3169-MSM1-P0-20UG
About this Product
- SKU:
- 3169-MSM1-P0
- Additional Names:
- Forkhead box protein A1 | Transcription factor 3A
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- FOXA1/1241
- Clonality:
- Monoclonal
- Extra Details:
- The transcription factor Forkhead-box A1 (FOXA1); also known as hepatocyte nuclear factor 3-alpha; is a member of the FOX class of transcription factors.HNF-1 (); and HNF-6 compose; in part; a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney; small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs; such as lung; pancreas; bladder; prostate; and colon. Recently; FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER)-positivity; especially in luminal subtype A breast cancers; which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.
- Host:
- Mouse
- Immunogen:
- Recombinant human FOXA1 protein fragment (aa372-472) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 49kDa
- Research Area:
- Cancer; Developmental Biology; Nuclear Marker; Signal Transduction; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115537
