CD168 / RHAMM Antibody
Product Sizes
20 ug
£364.00
3161-MSM1-P0-20UG
About this Product
- SKU:
- 3161-MSM1-P0
- Additional Names:
- Intracellular hyaluronic acid-binding protein | Receptor for hyaluronan-mediated motility
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- HMMR/8021
- Clonality:
- Monoclonal
- Extra Details:
- Hyaluronic acid (HA) is a nonsulfated glycosaminoglycan that regulates cell adhesion and migration. HA effects are mediated through two receptors; CD44 (also designated HCAM) and the receptor of hyaluronic acid mediated motility (RHAMM). RHAMM; also designated intracellular hyaluronic acid binding protein (IHABP) and CD168; is a matrix receptor; which is linked to the plasma membrane by a GPI anchor and regulates cell motility. RHAMM expression is upregulated in malignant lymphoid tissues and is subsequently implicated in tumor progression and metastasis formation; as well as signal transduction. Although still unclear; RHAMM is thought to exist as several isoforms ranging in size. A variant isoform; designated v4; is a protein that when over-expressed; is thought to be the cause of transformation and metastasis formation in fibroblasts.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-250) of human HMMR protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 85-90kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=135428
