MR1 / Major histocompatibility complex; class I-related Antibody
Product Sizes
100 ug
£671.00
3140-MSM3-P1-100UG
About this Product
- SKU:
- 3140-MSM3-P1
- Additional Names:
- Class I histocompatibility antigen-like protein
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MR1/7579
- Clonality:
- Monoclonal
- Extra Details:
- MR1 (major histocompatibility complex; class I-related); also known as HLALS; is a 341 amino acid single-pass membrane protein that localizes to the endoplasmic reticulum; as well as to the extracellular side of the cell membrane; and contains one Ig-like C1-type domain. Expressed ubiquitously; MR1 exists as a heterodimer with b-2-Microglobulin and plays an important role in antigen presentation; specifically in the development and expansion of mucosalassociated invariant T cells (MAITs). MAITs are located in the gut and are involved in monitoring flora levels; as well as in conveying distress signals to other areas of the body; indicating a role for MR1 in proper digestion and immune system function. MR1 exists as four alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 1.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa50-250) of human MR1 protein (exact sequence is proprietary)
- Isotype:
- IgG2
- Molecular Weight:
- 39kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=133566
