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Antibodies

HLA-DRB (MHC II) Antibody

Product Sizes
100 ug
£671.00
3123-MSM4-P1ABX-100UG
About this Product
SKU:
3123-MSM4-P1ABX
Additional Names:
Human leukocyte antigen DRB1
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
Bra30
Clonality:
Monoclonal
Extra Details:
This MAb reacts with the HLA-DRB3 antigen; a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells; activated T-cells; monocytes/macrophages; dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules; HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Host:
Mouse
Immunogen:
Human REH cells (non-T; non-B leukemia cell line)
Isotype:
IgG2a
Molecular Weight:
~28kDa (beta chain)
Research Area:
Cardiovascular; Cytokine Signaling; Dendritic Cell Marker; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody