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Antibodies

HLA-DRA (MHC II) Antibody

Product Sizes
100 ug
£671.00
3122-MSM2-P1-100UG
About this Product
SKU:
3122-MSM2-P1
Additional Names:
MHC class II antigen DRA
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
169-1B5.2
Clonality:
Monoclonal
Extra Details:
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells; activated T-cells; monocytes/macrophages; dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules; HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Host:
Mouse
Immunogen:
Human peripheral blood leukocytes
Isotype:
IgG2b
Molecular Weight:
36kDa (α chain) and 27kDa (β chain)
Research Area:
B Cell Markers; Cardiovascular; Cytokine Signaling; Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody