HLA-ABC (MHC I) Antibody
Product Sizes
20 ug
£364.00
3105-MSM2-P0-20UG
About this Product
- SKU:
- 3105-MSM2-P0
- Additional Names:
- Human leukocyte antigen B
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- Bra-23/9
- Clonality:
- Monoclonal
- Extra Details:
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A; B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate/tritiated sodium borohydride technique confirmed the structure gp44;p12 (consisting of a 44kDa glycopeptide linked with a non-glycosylated 12kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes; thymocytes; granulocytes; and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation; inhibition of NK cell cytotoxicity; tumor surveillance; and tissue allotransplantation.
- Host:
- Mouse
- Immunogen:
- Human REH cells (pre-B leukaemia cell line)
- Isotype:
- IgG2a
- Molecular Weight:
- ~41kDa
- Research Area:
- Immunology; Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=126792
