CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) Antibody
Product Sizes
100 ug
£671.00
30835-MSM4-P1-100UG
About this Product
- SKU:
- 30835-MSM4-P1
- Additional Names:
- C-type lectin domain family 4 member L | Dendritic cell-specific ICAM-3-grabbing non-integrin 1
- Application:
- Flow Cytometry
- translate.label.attr.clone:
- C209/6774
- Clonality:
- Monoclonal
- Extra Details:
- DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain; a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization; which allows the receptor to bind multivalent ligands with high avidity.
- Host:
- Mouse
- Immunogen:
- Recombinant human CD209 protein fragment (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 45kDa
- Research Area:
- Dendritic Cell Marker; Hematopoietic Stem Cells; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=115384
