KCNIP2 / KCHIP2 Antibody
Product Sizes
100 ug
£671.00
30819-MSM3-P1ABX-100UG
About this Product
- SKU:
- 30819-MSM3-P1ABX
- Additional Names:
- A-type potassium channel modulatory protein 2 | Cardiac voltage-gated potassium channel modulatory subunit | Potassium channel-interacting protein 2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- KCNIP2/7589
- Clonality:
- Monoclonal
- Extra Details:
- In the brain and heart; rapidly inactivating (A-type) voltage-gated potassium (Kv) currents control the excitability of neurons and cardiac myocytes. KChIPs are Kv channel-interacting proteins that bind to the cytoplasmic amino termini of Kv4α-subunits and are integral components of native Kv4 channel complexes. KChIP family members include KChIP1 expressed in brain; KChIP2 expressed in heart; brain; and lung; and KChIP3 (previously identified as calsenilin) expressed in brain and testis. In rat brain; KChIP1 colocalizes with Kv4.3 in granule cells and KChIP2 colocalizes with Kv4.2 in both neocoritcal and subcortical structures. The KChIPs are members of the recoverin/neuronal calcium sensor-1 subfamily of calcium-binding proteins and show 99% nucleotide homology to DREAM; suggesting that KChIPs may have activity beyond modulation of Kv4 channels.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa1-270) of human KCNIP2 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 27-36kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=135078
